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NHS Arden and Greater East Midlands Commissioning Support Unit (AGCSU), on behalf of NHS England (referred to as the Commissioner), invited suitably qualified and experienced providers to respond to a Competitive Process for the provision of Tumour Infiltrating Lymphocyte (TIL) Therapy hubs for Melanoma (Adults). <br/><br/>Lifileucel is a first in class autologous tumour infiltrating lymphocyte (TIL) cell therapy. This infusion is followed by a short course of interleukin-2 (IL-2). IL-2 is a potent drug and has the potential to cause significant side effects. As such, it is recommended that patients receive treatment at a trust with immediate access to an Intensive Therapy<br/>Unit (ITU).<br/><br/>Lifileucel is being assessed via NICE’s technology appraisal programme for previously treated unresectable or metastatic melanoma in adults, with an expected final guidance publication date in 2026 in line with NICE guidance: https://www.nice.org.uk/guidance/indevelopment/gid-ta10752<br/><br/>The treatment is complex to administer, requiring surgical expertise for tumour<br/>resection, melanoma expertise for patient selection and management post-treatment and cell therapy expertise to administer the cell therapy and manage the side effects and associated care of both Lifileucel and IL-2 administration.<br/><br/>The key objective of the Procurement was to commission Tumour Infiltrating Lymphocyte (TIL)Therapy Hubs for adult patients across the following seven (7) geographical regions to serve the population of England:<br/>Lot 1: London<br/>Lot 2: East of England<br/>Lot 3: South East<br/>Lot 4: South West<br/>Lot 5: Midlands<br/>Lot 6: North East and Yorkshire<br/>Lot 7: North West<br/><br/>This process was designed to enable any provider meeting the required standards to be awarded a contract, with no restriction on the number of sites commissioned.<br/><br/>As a result of this procurement exercise the commissioner intends to award 12 separate contracts across the 7 Lots.<br/><br/>The service is due to commence on 1st May 2025, subject to NICE guidance, for a period of 5 years with the Commissioners having the option to extend for up to an additional 4 year(s)(maximum contract duration 9 years).
| Supplier | Identifier | Award Value | Lots Won | Cross-References |
|---|---|---|---|---|
| Barts Health NHS Trust | - | £11,876,000 | 1 lot Lot 3: South East | - |
| Cambridge University Hospitals NHS Foundation Trust | - | £11,876,000 | 1 lot Lot 5: Midlands | - |
| Guy's and St Thomas' NHS Foundation Trust | - | £11,876,000 | 1 lot Lot 2 - East of England | - |
| Oxford University Hospitals NHS FT | - | £11,876,000 | 1 lot Lot 6: North East & Yorkshire | - |
| The Christie NHS Foundation Trust | - | £11,876,000 | - | - |
| THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST | - | £11,876,000 | - | - |
| The Newcastle upon Tyne Hospitals NHS Foundation Trust | - | £11,876,000 | - | - |
| The Royal Marsden NHS Foundation Trust | - | £11,876,000 | 1 lot Lot 4: South West | - |
| University College London Hospitals NHS Foundation Trust | - | £11,876,000 | 1 lot Lot 1 - London | - |
| University Hospitals Bristol and Weston NHS Foundation Trust | - | £11,876,000 | - | - |
| UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST | - | £11,876,000 | - | - |
| University Hospitals Southampton | - | £11,876,000 | 1 lot Lot 7: North West | - |
Taken from this notice, not from Companies House. Check the original notice — details change and are not updated here.
This procurement was divided into 7 lots, each awarded separately. 32 bids were received in total.
| Lot | Value | Awarded To | Status |
|---|---|---|---|
| Lot 1 Lot 1 - London 3,120 days (≈8.5 yrs) | £142,512,000 £11,876,000 initial term | University College London Hospitals NHS Foundation Trust | active |
| Lot 2 Lot 2 - East of England | £11,876,000 initial term | Guy's and St Thomas' NHS Foundation Trust | active |
| Lot 3 Lot 3: South East | £11,876,000 initial term | Barts Health NHS Trust | active |
| Lot 4 Lot 4: South West | £11,876,000 initial term | The Royal Marsden NHS Foundation Trust | active |
| Lot 5 Lot 5: Midlands | £11,876,000 initial term | Cambridge University Hospitals NHS Foundation Trust | active |
| Lot 6 Lot 6: North East & Yorkshire | £11,876,000 initial term | Oxford University Hospitals NHS FT | active |
| Lot 7 Lot 7: North West | £11,876,000 initial term | University Hospitals Southampton | active |
Weightings from the notice, applied to every lot.
Published by the buyer on this notice. Check the original notice — details change and are not updated here.